CD102 (ICAM-2) antibodies, human

CD102 (ICAM-2) antibodies, human

Clone: REA878 | Dilution: 1:50
Clone REA878 recognizes the human CD102 antigen, a type I transmembrane glycoprotein with two immunoglobulin-like domains. CD102, also known as ICAM-2, is a member of the intercellular adhesion molecule (ICAM) family, that binds to leukocyte integrin, lymphocyte function-associated antigen-1 (LFA-1), dendritic cell-specific antigen, ICAM-grabbing non-integrin (DC-SIGN) protein and macrophage-1 antigen (MAC-1). CD102 is found on vascular endothelial cells, monocytes, platelets and different populations of lymphocytes..
CD102 is involved in lymphocyte recirculation and induces essential adhesive cell interactions, which are important for immune response and surveillance.
Additional information: Clone REA878 displays negligible binding to Fc receptors.

Alternative names

ICAM-2

Technical specifications

  • Antigen: CD102 (ICAM-2)
  • Clone: REA878
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ICAM-2
  • Entrez Gene ID: 3384
  • Molecular mass of antigen [kDa]: 55
  • Distribution of antigen: endothelial cells, monocytes, platelets, lymphocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, APC-Vio770
  • Selected references

    1. Staunton, D. E. et al. (1989) Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1. Nature 339(6219): 61-64
    2. Simmons, D. L. (1995) The role of ICAM expression in immunity and disease. Cancer Surv. 24: 144-155
    3. Weber, K. S. et al. (2004) Sialylation of ICAM-2 on platelets impairs adhesion of leukocytes via LFA-1 and DC-SIGN. Inflammation 28(4): 177-188
Product options: 8
130-114-411

CD102 (ICAM-2)-PE, human

for 30
tests
(1)
-
130-114-304

CD102 (ICAM-2)-PE, human

for 100
tests
(1)
-
130-114-412

CD102 (ICAM-2)-APC, human

for 30
tests
(1)
-
130-114-305

CD102 (ICAM-2)-APC, human

for 100
tests
(1)
-
130-114-413

CD102 (ICAM-2)-PE-Vio770, human

for 30
tests
(1)
-
130-114-306

CD102 (ICAM-2)-PE-Vio770, human

for 100
tests
(1)
-
130-114-414

CD102 (ICAM-2)-APC-Vio770, human

for 30
tests
(1)
-
130-114-307

CD102 (ICAM-2)-APC-Vio770, human

for 100
tests
(1)
-