CD101 antibodies, human

CD101 antibodies, human

Clone: REA954 | Dilution: 1:50
Clone REA954 recognizes the human CD101 antigen, also known as V7 or IGSF2, which is a 140 kDa type I transmembrane glycoprotein of the Ig gene superfamily. CD101 is expressed on monocytes, granulocytes, and subsets of dendritic cells (DCs). In addition, CD101 is expressed on certain subpopulations of T cells, in particular about 5–30% of FoxP3
+
Treg cells in peripheral blood. The interaction of CD101 with clone REA954 has been shown to inhibit T cell activation by allogeneic DCs or CD3 antibodies.
Additional information: Clone REA954 displays negligible binding to Fc receptors.

Alternative Names

EWI-101, IGSF2, V7, p126

Technical specifications

  • Antigen: CD101
  • Clone: REA954
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: EWI-101, IGSF2, V7, p126
  • Entrez Gene ID: 9398
  • Molecular mass of antigen [kDa]: 113
  • Distribution of antigen: dendritic cells, granulocytes, monocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, VioBright 515, Biotin
  • Selected references

    1. Rivas, A. et al. (1995) V7, a novel leukocyte surface protein that participates in T cell activation. J. Immunol. 154: 4423-4433
    2. Soares, L. R. et al. (1998)
      V7 (CD101) ligation inhibits TCR/CD3-induced IL-2 production by blocking Ca
      2+
      flux and nuclear factor of activated T cell nucleartranslocation.
      J. Immunol. 161: 209-217
    3. Bouloc, A. et al. (2000) Triggering CD101 molecule on human cutaneous dendritic cells inhibits T cell proliferation via IL-10 production. Eur. J. Immunol. 30: 3132-3139

Related products

3 products available
Product options: 12
130-115-902

CD101-PE, human

for 30
tests
(1)
-
130-115-830

CD101-PE, human

for 100
tests
(1)
-
130-115-903

CD101-APC, human

for 30
tests
(1)
-
130-115-831

CD101-APC, human

for 100
tests
(1)
-
130-115-907

CD101-PE-Vio615, human

for 30
tests
(1)
-
130-115-835

CD101-PE-Vio615, human

for 100
tests
(1)
-
130-115-904

CD101-PE-Vio770, human

for 30
tests
(1)
-
130-115-832

CD101-PE-Vio770, human

for 100
tests
(1)
-
130-115-906

CD101-VioBright 515, human

for 30
tests
(1)
-
130-115-834

CD101-VioBright 515, human

for 100
tests
(1)
-
130-115-900

CD101-Biotin, human

for 30
tests
(1)
-
130-115-828

CD101-Biotin, human

for 100
tests
(1)
-