Anti-TROP2 antibodies, human

Anti-TROP2 antibodies, human

Clone: REA916 | Dilution: 1:50
Clone REA916 recognizes the human TROP2 antigen, a type I membrane glycoprotein also known as tumor-associated calcium signal transducer 2 (TACSTD2). TROP2 acts as a signal transducer and may be involved in regulating the growth of carcinoma cells. It is strongly expressed by a variety of human carcinomas, but also on trophoblasts and epithelial cells.
Additional information: Clone REA916 displays negligible binding to Fc receptors.

Alternative Names

TACSTD2, GA733-1, M1S1, TROP2, EGP-1

Technical specifications

  • Antigen: TROP2
  • Clone: REA916
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TACSTD2, GA733-1, M1S1, TROP2, EGP-1
  • Entrez Gene ID: 4070
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: placenta, pancreatic carcinoma cells, epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Fornaro, M. et al. (1995) Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas. Int. J. Cancer 62(5): 610-618
    2. Ripani, E. et al. (1998) Human Trop-2 is a tumor-associated calcium signal transducer. Int. J. Cancer 76(5): 671-676
    3. Cubas, R. et al. (2010) Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway. Mol. Cancer 9(253)
Product options: 8
130-115-343

Anti-TROP2-FITC, human

for 30
tests
(1)
-
130-115-244

Anti-TROP2-FITC, human

for 100
tests
(1)
-
130-115-097

Anti-TROP2-PE, human

for 30
tests
(1)
-
130-115-055

Anti-TROP2-PE, human

for 100
tests
(1)
-
130-115-098

Anti-TROP2-APC, human

for 30
tests
(1)
-
130-115-056

Anti-TROP2-APC, human

for 100
tests
(1)
-
130-115-096

Anti-TROP2-Biotin, human

for 30
tests
(1)
-
130-115-054

Anti-TROP2-Biotin, human

for 100
tests
(1)
-