Anti-TRA-1-60 antibodies, human

Anti-TRA-1-60 antibodies, human

Clone: REA157 | Dilution: 1:11
Clone REA157 recognizes the TRA-1-60 antigen, a neuraminidase-resistant carbohydrate epitope expressed on podocalyxin, which is a transmembrane glycoprotein. Podocalyxin is a member of the CD34-related family of sialomucins and is recognized as a stem cell and tumor marker. TRA-1-60 antigen is expressed on the surface of human embryonic stem cells (ESC), embryonic germ cells (EG), and embryonic carcinoma cells (EC). Expression of TRA-1-60 is lost upon differentiation and thus it can be used to assess the differentiation stage of the cells. TRA-1-60 can be detected in the serum of patients with germ cell tumors which contain an EC component.
Additional information: Clone REA157 displays negligible binding to Fc receptors.

Alternative Names

PODXL, Gp200, PC, PCLP, PCLP-1, Podocalyxin

Technical specifications

  • Antigen: TRA-1-60
  • Clone: REA157
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: PODXL, Gp200, PC, PCLP, PCLP-1, Podocalyxin
  • Distribution of antigen: ES and iPS cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
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