Anti-TNF-α antibodies, mouse

Anti-TNF-α antibodies, mouse

Clone: MP6-XT22 | Dilution: 1:10
Mouse tumor necrosis factor α (TNF-α) is secreted by macrophages, monocytes, neutrophils, CD4
+
T cells, and NK cells. It has cytolytic activity against a range of tumor cells and is important in immune regulation. TNF-α binding to surface receptors elicits a wide array of biologic activities, including cytolysis and cytostasis of many tumor cell lines
in vitro
, hemorraghic necrosis of tumors
in vivo
, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.

Alternative Names

TNF, DIF, TNFSF2, Tnfsf1a

Technical specifications

  • Antigen: TNF-α
  • Clone: MP6-XT22
  • Isotype: rat IgG1κ
  • Isotype control: Rat IgG1 – isotype control antibodies
  • Alternative names of antigen: TNF, DIF, TNFSF2, Tnfsf1a
  • Entrez Gene ID: 21926
  • Molecular mass of antigen [kDa]: 26
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
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