Anti-TIM-3 antibodies, mouse

Anti-TIM-3 antibodies, mouse

Clone: RMT3-23 | Dilution: 1:10
The monoclonal antibody RMT3-23 reacts with mouse TIM-3, which is a Th-1-specific cell surface protein expressed by differentiated CD4
+
Th1 and CD8
+
Tc1 cells and macrophages. It is absent on CD4
+
Th2 and CD8
+
Tc2 cells. TIM-3 has been proposed to inhibit Th1-mediated immune responses. TIM-3 absence enhances the severity of experimental autoimmune encephalomyelitis in mice. The interaction of TIM-3 and Galectin-9 induces apoptosis of Th1 cells.

Alternative Names

HAVCR2, TIMD-3, Tim3

Technical specifications

  • Antigen: TIM-3
  • Clone: RMT3-23
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: HAVCR2, TIMD-3, Tim3
  • Entrez Gene ID: 171285
  • Molecular mass of antigen [kDa]: 29
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
Product options: 3

Product information

Size
Order no.
Price

Anti-TIM-3-PE, mouse

  • RMT3-23
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-415
-

Anti-TIM-3-APC, mouse

  • RMT3-23
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-366
-

Anti-TIM-3-Biotin, mouse

  • RMT3-23
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-101-890
-

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