Anti-TIM-3 antibodies, mouse

Anti-TIM-3 antibodies, mouse

Clone: REA602 | Dilution: 1:10
Clone REA602 reacts with the mouse TIM-3 antigen, which is a Tʜ1-specific cell surface protein expressed by differentiated CD4
+
Tʜ1 and CD8
+
Tc1 cells and macrophages. It is absent on CD4
+
Tʜ2 and CD8
+
Tc2 cells. TIM-3 has been proposed to inhibit Tʜ1-mediated immune responses. TIM-3 absence enhances the severity of experimental autoimmune encephalomyelitis in mice. The interaction of TIM-3 and Galectin-9 induces apoptosis of Tʜ1 cells.
Additional information: Clone REA602 displays negligible binding to Fc receptors.

Alternative Names

Tim3

Technical specifications

  • Antigen: TIM-3
  • Clone: REA602
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Tim3
  • Entrez Gene ID: 171285
  • Molecular mass of antigen [kDa]: 29
  • Distribution of antigen: macrophages
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, APC, Biotin
Product options: 6

Product information

Size
Order no.
Price

Anti-TIM-3-VioBright FITC, mouse

  • REA602
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-528
-

Anti-TIM-3-VioBright FITC, mouse

  • REA602
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-449
-

Anti-TIM-3-APC, mouse

  • REA602
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-527
-

Anti-TIM-3-APC, mouse

  • REA602
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-448
-

Anti-TIM-3-Biotin, mouse

  • REA602
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-525
-

Anti-TIM-3-Biotin, mouse

  • REA602
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-446
-

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