Anti-TIM-3 antibodies, human

Anti-TIM-3 antibodies, human

Clone: F38-2E2 | Dilution: 1:50
The monoclonal antibody F38-2E2 recognizes human cell surface molecule TIM-3, which is expressed on activated T cells, especially Tʜ1 cells, monocytes, macrophages, and dendritic cells. TIM-3 has been proposed to inhibit Tʜ1-mediated immune responses and regulates Tʜ1 and Tʜ17 cytokine secretion. The interaction of TIM-3 and its ligand galectin-9 induces apoptosis of Tʜ1 cells.

Alternative Names

HAVCR2, CD366, HAVcr-2, KIM-3, TIMD-3

Technical specifications

  • Antigen: TIM-3
  • Clone: F38-2E2
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: HAVCR2, CD366, HAVcr-2, KIM-3, TIMD-3
  • Entrez Gene ID: 84868
  • Molecular mass of antigen [kDa]: 31
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
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