Anti-TCR Vδ1 antibodies, human

Anti-TCR Vδ1 antibodies, human

Clone: REA173 | Dilution: 1:50
Clone REA173 recognizes the Vδ1 chain of γδ T cell receptor (TCR). The TCR δ locus is located within the TCR α locus on chromosome 14 and 6 Vδ segments have been reported so far. γδ T cells comprise a small population of T cells and unlike peripheral circulating αβ T cells, γδ T cells are mainly found in body tissues such as thymus, peripheral lymphoid tissues, intestinal epithelium, and epidermis. Distribution analysis in human oral cavity revealed preferential localisation of Vδ1
γδ T cells in intraepithelial region.
Additional information: Clone REA173 displays negligible binding to Fc receptors.

Alternative Names

TRDV1, hDV101S1

Technical specifications

  • Antigen: TCR Vδ1
  • Clone: REA173
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TRDV1, hDV101S1
  • Entrez Gene ID: 28518
  • Distribution of antigen: T cells, epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, APC
REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the other known clones. 
Other clonesOverlap in epitope recognition with REA173

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