Anti-TCR Vβ8.1, 8.2 antibodies, mouse

Anti-TCR Vβ8.1, 8.2 antibodies, mouse

Clone: REA585 | Dilution: 1:10
Clone REA585 recognizes the mouse Vβ8.1, 8.2 T cell receptor (TCR Vβ8.1, 8.2) but not Vβ8.3. Vβ8.1 and 8.2 are variants of the TCR β chain that associates with the TCR α chain. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains. TCR Vβ8.1, 8.2 is expressed on approximately 20 % of peripheral T cells in thymus, spleen, and other lymphoid organs in different mice strains, such as Balb/c, AKR, C57BL/6, AKR/B10.A.
Additional information: Clone REA585 displays negligible binding to Fc receptors

Alternative Names

TCR Vb8.1, 8.2, TCR Vbeta8.1, 8.2

Technical specifications

  • Antigen: TCR Vβ8.1, 8.2
  • Clone: REA585
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TCR Vb8.1, 8.2, TCR Vbeta8.1, 8.2
  • Entrez Gene ID: 100124677, 100124675
  • Molecular mass of antigen [kDa]: 13
  • Distribution of antigen: T cells, spleen
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected References

    1. Haskins, K. et al. (1984) The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J. Exp. Med. 160(2): 452-471
    2. Kuchroo, V. K. et al. (1994) T cell receptor (TCR) usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with TCR V beta 8.2 transgenic mice. J. Exp. Med. 179(5): 1659-1664
    3. Mami-Chouaib, F. et al. (2002) Antitumor cytotoxic T-lymphocyte response in human lung carcinoma: identification of a tumor-associated antigen. Immunol. Rev. 188: 114-121
Product options: 12

Product information

Size
Order no.
Price

Anti-TCR Vβ8.1, 8.2-FITC, mouse

  • REA585
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-079
-

Anti-TCR Vβ8.1, 8.2-FITC, mouse

  • REA585
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-024
-

Anti-TCR Vβ8.1, 8.2-PE, mouse

  • REA585
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-080
-

Anti-TCR Vβ8.1, 8.2-PE, mouse

  • REA585
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-025
-

Anti-TCR Vβ8.1, 8.2-APC, mouse

  • REA585
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-081
-

Anti-TCR Vβ8.1, 8.2-APC, mouse

  • REA585
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-026
-

Anti-TCR Vβ8.1, 8.2-PE-Vio770, mouse

  • REA585
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-082
-

Anti-TCR Vβ8.1, 8.2-PE-Vio770, mouse

  • REA585
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-027
-

Anti-TCR Vβ8.1, 8.2-APC-Vio770, mouse

  • REA585
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-083
-

Anti-TCR Vβ8.1, 8.2-APC-Vio770, mouse

  • REA585
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-028
-

Anti-TCR Vβ8.1, 8.2-Biotin, mouse

  • REA585
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-078
-

Anti-TCR Vβ8.1, 8.2-Biotin, mouse

  • REA585
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-023
-