Anti-Siglec-8 antibodies, human

Anti-Siglec-8 antibodies, human

Clone: 7C9 | Dilution: 1:11
The monoclonal antibody 7C9 recognizes siglec-8, a 54 kDa type I transmembrane protein, which is a member of the Ig superfamily. Though it is mainly expressed by eosinophils, expression of siglec-8 is also found on basophils and mast cells. It has been reported that siglec-8 cross-linking with antibodies reduces eosinophil viability through induction of apoptosis.

Alternative Names

SAF2, SIGLEC8L

Technical specifications

  • Antigen: Siglec-8
  • Clone: 7C9
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: SAF2, SIGLEC8L
  • Entrez Gene ID: 27181
  • Molecular mass of antigen [kDa]: 52
  • Distribution of antigen: B cells, bone marrow, granulocytes, leukocytes, liver, monocytes, neutrophils, NK cells, placenta, spleen, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, Biotin
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