Anti-ROR1 antibodies, human

Anti-ROR1 antibodies, human

Clone: REA1051 | Dilution: 1:50
Clone REA1051 recognizes the human ROR1 antigen, also known as receptor tyrosine kinase-like orphan receptor 1. ROR1 has characteristics of an oncofetal gene and was recently identified to be overexpressed at the gene and protein levels in chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). ROR1 expression has also been detected in ovarian cancer, renal cancer, melanoma, and lung adenocarcinoma, suggesting a general role of ROR1 in cancer genesis and/or maintenance. Moreover, ROR1 expression has been found in undifferentiated embryonic stem cells, in adipose tissue, at early stages of B cell development, but not in major adult tissues. Therefore, ROR1 is a potential therapeutic target and a biomarker to identify and enumerate malignant cells in CLL and MCL blood samples via flow cytometry.
Additional information: Clone REA1051 displays negligible binding to Fc receptors.

Alternative Names

NTRKR1

Technical specifications

  • Antigen: ROR1
  • Clone: REA1051
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: NTRKR1
  • Entrez Gene ID: 4919
  • Molecular mass of antigen [kDa]: 101
  • Distribution of antigen: tumor cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, APC, PE-Vio615, VioBright 515, Biotin

Related products

3 products available
Product options: 8

Product information

Size
Order no.
Price

Anti-ROR1-APC, human

  • REA1051
  • 1:50
  • For research use only
for 30
tests
(1)
130-118-015
-

Anti-ROR1-APC, human

  • REA1051
  • 1:50
  • For research use only
for 100
tests
(1)
130-117-942
-

Anti-ROR1-PE-Vio615, human

  • REA1051
  • 1:50
  • For research use only
for 30
tests
(1)
130-118-016
-

Anti-ROR1-PE-Vio615, human

  • REA1051
  • 1:50
  • For research use only
for 100
tests
(1)
130-117-943
-

Anti-ROR1-VioBright 515, human

  • REA1051
  • 1:50
  • For research use only
for 30
tests
(1)
130-118-017
-

Anti-ROR1-VioBright 515, human

  • REA1051
  • 1:50
  • For research use only
for 100
tests
(1)
130-117-944
-

Anti-ROR1-Biotin, human

  • REA1051
  • 1:50
  • For research use only
for 30
tests
(1)
130-118-018
-

Anti-ROR1-Biotin, human

  • REA1051
  • 1:50
  • For research use only
for 100
tests
(1)
130-117-945
-