Anti-Rae-1 Pan Specific antibodies, mouse

Anti-Rae-1 Pan Specific antibodies, mouse

Clone: REA723 | Dilution: 1:50
Clone REA723 recognizes the Rae-1 pan specific antigen, a surface protein and member of GPI-linked (glypiated) proteins which share partial homology with MHC class I molecules. Rae-1 was detected in early mouse embryos, especially in the head region. Rae-1 is also up-regulated on a large variety of tumor cells. Together with H-60, Rae-1 is a ligand for the murine NKG2D receptor and a potent stimulator of innate immunity. The ligand-expressing tumor cells induce potent priming of cytotoxic T cells and sensitization of NK cells
in vivo
. Clone REA723 detects Rae-1α/β/γ/δ/ε.
Additional information: Clone REA723 displays negligible binding to Fc receptors.

Alternative Names

mRNA export factor, Rae1, Mrnp41

Technical specifications

  • Antigen: Rae-1 Pan Specific
  • Clone: REA723
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: mRNA export factor, Rae1, Mrnp41
  • Entrez Gene ID: 66679
  • Molecular mass of antigen [kDa]: 41
  • Distribution of antigen: T cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected References

    1. Nomura, M. et al. (1996) Genomic structures and characterization of Rae1 family members encoding GPI-anchored cell surface proteins and expressed predominantly in embryonic mouse brain. J. Biol. Chem. 120(5): 987-995
    2. Diefenbach, A. et al. (2000) Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nat. Immunol. 1(2): 119-126
    3. Diefenbach, A. et al. (2001) Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity. Nature 413(6852): 165-171
Product options: 10

Product information

Size
Order no.
Price

Anti-Rae-1 Pan Specific-FITC, mouse

  • REA723
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-468
-

Anti-Rae-1 Pan Specific-PE, mouse

  • REA723
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-469
-

Anti-Rae-1 Pan Specific-PE, mouse

  • REA723
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-111-283
-

Anti-Rae-1 Pan Specific-APC, mouse

  • REA723
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-470
-

Anti-Rae-1 Pan Specific-APC, mouse

  • REA723
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-111-284
-

Anti-Rae-1 Pan Specific-PE-Vio770, mouse

  • REA723
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-471
-

Anti-Rae-1 Pan Specific-APC-Vio770, mouse

  • REA723
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-472
-

Anti-Rae-1 Pan Specific-PerCP-Vio700, mouse

  • REA723
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-473
-

Anti-Rae-1 Pan Specific-Biotin, mouse

  • REA723
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-467
-

Anti-Rae-1 Pan Specific-Biotin, mouse

  • REA723
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-111-281
-