Anti-p70 S6 Kinase antibodies, human, mouse, rat

Anti-p70 S6 Kinase antibodies, human, mouse, rat

Clone: REA843 | Dilution: 1:50
Clone REA843 recognizes the intracellular p70 S6 Kinase, also known as ribosomal protein S6 kinase beta-1. It is a serine/threonine kinase that is widely expressed in the cytosol and in the nucleus. It mediates cell cycle progression and is involved in the regulation of protein synthesis. The p70 S6 kinase is localized in cytosol and in the nucleus, after cytokine stimulation. TNF-receptor activation leads to activation of the p70 S6 kinase, which increases protein synthesis and cell proliferation. In addition, p70 S6 kinase is a major effector of mammalian target of rapamycin (mTOR) phosphorylation.
Additional information: Clone REA843 displays negligible binding to Fc receptors.

Alternative Names

S6K-beta-1, S6K1, P70S6K1, p70-S6K 1

Technical specifications

  • Antigen: p70 S6 Kinase
  • Clone: REA843
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: S6K-beta-1, S6K1, P70S6K1, p70-S6K 1
  • Entrez Gene ID: 6198, 72508, 83840
  • Molecular mass of antigen [kDa]: 59
  • Distribution of antigen: ubiquitous
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Vio515
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