Anti-OTX2 antibodies, human

Anti-OTX2 antibodies, human

Clone: REA1178 | Dilution: 1:50
Clone REA1178 recognizes the human orthodenticle 2 (OTX2) protein, which is a member of the bicoid sub-family of homeodomain-containing transcription factors. OTX2 is expressed on pluripotent stem cells and differentiated cells in brain, ear, nose, and eye. It plays an essential role in proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis and is involved in brain, craniofacial, and sensory organ development.
Additional information: Clone REA1178 displays negligible binding to Fc receptors.

Alternative names

orthodenticle 2

Technical specifications

  • Antigen: OTX2
  • Clone: REA1178
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: orthodenticle 2
  • Entrez Gene ID: 5015
  • Molecular mass of antigen [kDa]: 32
  • Distribution of antigen: brain, eye, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, Vio515
  • Selected references

    1. Gorbenko Del Blanco, D. et al. (2012) A novel OTX2 mutation in a patient with combined pituitary hormone deficiency, pituitary malformation, and an underdeveloped left optic nerve. Eur. J. Endocrinol. 167(3): 441-452
    2. Nagao, T. et al. (1998)
      Developmental rescue of
      Drosophila cephalic
      defects by the human OTX genes.
      Proc. Natl. Acad. Sci. U.S.A. 95(7): 3737-3742
Product options: 6
130-121-195

Anti-OTX2-FITC, human

for 30
tests
(1)
-
130-121-186

Anti-OTX2-FITC, human

for 100
tests
(1)
-
130-121-196

Anti-OTX2-PE, human

for 30
tests
(1)
-
130-121-187

Anti-OTX2-PE, human

for 100
tests
(1)
-
130-121-202

Anti-OTX2-Vio515, human

for 30
tests
(1)
-
130-121-193

Anti-OTX2-Vio515, human

for 100
tests
(1)
-