Anti-Notch2 antibodies, mouse

Anti-Notch2 antibodies, mouse

Clone: HMN2-35 | Dilution: 1:10
Clone HMN2-35 recognizes Notch2, a member of the Notch receptor family. Notch2 acts as a receptor for the membrane bound ligands Jagged1, Jagged2 and Delta1. Notch signaling pathway is evolutionary conserved in the animal kingdom, where Notch receptors upon ligand binding undergo two proteolytic cleavages. The second cleavage releases the Notch intracellular domain (NICD), which translocates into the nucleus, forms an activator complex with the DNA binding protein RBP-J and activates genes of the enhancer of split locus. Notch signaling network regulates a number of biological processes involved in determination of cell fate, cell differentiation and apoptosis etc.

Alternative Names

N2

Technical specifications

  • Antigen: Notch2
  • Clone: HMN2-35
  • Isotype: hamster IgG
  • Alternative names of antigen: N2
  • Entrez Gene ID: 18129
  • Molecular mass of antigen [kDa]: 263
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
Product options: 6

Product information

Size
Order no.
Price

Anti-Notch2-PE, mouse

  • HMN2-35
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-102-854
-

Anti-Notch2-PE, mouse

  • HMN2-35
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-369
-

Anti-Notch2-APC, mouse

  • HMN2-35
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-102-853
-

Anti-Notch2-APC, mouse

  • HMN2-35
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-321
-

Anti-Notch2-Biotin, mouse

  • HMN2-35
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-102-002
-

Anti-Notch2-Biotin, mouse

  • HMN2-35
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-101-880
-