Anti-MHC Class II (I-Ek) antibodies, mouse and rat

Anti-MHC Class II (I-Ek) antibodies, mouse and rat

Clone: REA510 | Dilution: 1:10
Clone REA510 recognizes the mouse MHC class II alloantigen I-Ek. It also recognizes the rat MHC class II antigen RT1D and cells from mice of the H-2
d
, H-2
p
, and H-2
r
haplotypes. Cells from mice of the H-2
b
, H-2
f
, H-2
g7
, H-2
q
, and H-2
s
haplotypes do not express the I-E antigen. MHC class II is expressed on antigen-presenting cells, such as dendritic cells, monocytes, macrophages, B cells in lymphoid and non-lymphoid tissue, thymic epithelial cells, and on subsets of hematopoietic progenitor cells in the bone marrow.
Additional information: Clone REA510 displays negligible binding to Fc receptors.

Alternative Names

RT1D

Technical specifications

  • Antigen: MHC Class II (I-Ek)
  • Clone: REA510
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: RT1D
  • Entrez Gene ID: 14969, 294270
  • Molecular mass of antigen [kDa]: 27
  • Distribution of antigen: B cells, dendritic cells, hematopoietic stem cells, macrophages, monocytes, thymic epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, VioBright FITC, PE, APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
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