Anti-Ly-49G2 antibodies, mouse

Anti-Ly-49G2 antibodies, mouse

Clone: REA1053 | Dilution: 1:50
Clone REA1053 recognizes Ly-49G2, which is a inhibitory receptor specific for class Ia MHC molecules. Ly-49G2 belongs to the Ly-49 multigene family, which consists of type II transmembrane homodimeric receptors. Inhibitory Ly-49 members such as Ly-49G2 contain immunoreceptor tyrosine-based inhibitory motif (ITIM) 3 in their cytoplasmic tail and transduce signal that prevents the NK cell cytolytic activity upon recognizing ligands such as H-2Ddk. Expression of Ly-49G2 is found on subsets of natural killer (NK) cells, NK-T cells, and on a population of memory CD8
+
T cells (in C57BL/6 mice).
Additional information: Clone REA1053 displays negligible binding to Fc receptors

Alternative Names

Klra7, LGL-1, Ly49G.4, Ly-49G, Ly49g1, Ly-49G2

Technical specifications

  • Antigen: Ly-49G2
  • Clone: REA1053
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Klra7, LGL-1, Ly49G.4, Ly-49G, Ly49g1, Ly-49G2
  • Entrez Gene ID: 16638
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, VioBright 515, Biotin
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