Anti-Ly-49F antibodies, mouse

Anti-Ly-49F antibodies, mouse

Clone: REA1021 | Dilution: 1:50
Clone REA1021 recognizes the mouse Ly-49F antigen (killer cell lectin-like receptor 6), a type II transmembrane natural killer (NK) cell receptor belonging to the Ly-49 family. Members of the Ly-49 family are homodimeric C-type lectin receptors, recognizing MHC class I molecules as ligands and include activating and inhibitory receptor molecules. The inhibitory receptor Ly-49F is expressed on subsets of NK cells, NK-T cells, and on a subpopulation of memory T cells in C57BL/6 mice, but not AKR/J, BALB/c, C3H/HeN, DBA/1, or SJL mice. IL-21 selectively down-regulates Ly-49F on mature NK cells.
Additional information: Clone REA1021 displays negligible binding to Fc receptors.

Alternative Names

Klra6, Lymphocyte antigen 49f, T-cell surface glycoprotein Ly-49F

Technical specifications

  • Antigen: Ly-49F
  • Clone: REA1021
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Klra6, Lymphocyte antigen 49f, T-cell surface glycoprotein Ly-49F
  • Entrez Gene ID: 16637
  • Molecular mass of antigen [kDa]: 31
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
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