Anti-Ly-49D antibodies, mouse

Anti-Ly-49D antibodies, mouse

Clone: REA1020 | Dilution: 1:50
Clone REA1020 recognizes Ly-49D, a type II transmembrane NK cell receptor belonging to the Ly-49 family. Members of the Ly-49 family are homodimeric C-type lectin receptors, recognizing MHC class I molecules as ligands, and include activating and inhibitory receptor molecules. Ly-49D is a prototypic activating member of the Ly-49 family and in contrast to inhibitory members, lacks a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM). A positive signal is initiated by interaction of Ly-49D with immunoreceptor tyrosine-based activating motif (ITAM) containing transmembrane adapter DAP12. Expression of Ly-49D is strain restricted and is found on subsets of NK cells in C57BL/6, C3H/He, and SJL but not in BALB/c, DBA/2, AKR, and CBA/J mice.
Additional information: Clone REA1020 displays negligible binding to Fc receptors.

Alternative Names

Klra4, Chok, Klra32, Klra33, Ly-49d

Technical specifications

  • Antigen: Ly-49D
  • Clone: REA1020
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Klra4, Chok, Klra32, Klra33, Ly-49d
  • Entrez Gene ID: 16635
  • Molecular mass of antigen [kDa]: 31
  • Distribution of antigen: dendritic cells, macrophages, NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC

Related products

2 products available
Product options: 4

Product information

Size
Order no.
Price

Anti-Ly-49D-PE, mouse

  • REA1020
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-253
-

Anti-Ly-49D-PE, mouse

  • REA1020
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-117-162
-

Anti-Ly-49D-APC, mouse

  • REA1020
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-254
-

Anti-Ly-49D-APC, mouse

  • REA1020
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-117-163
-