Anti-Ki-67 antibodies, human and mouse

Anti-Ki-67 antibodies, human and mouse

Clone: REA183 | Dilution: 1:50
Clone REA183 recognizes the Ki-67 antigen, a nuclear and nucleolar protein, which is strictly associated with cell proliferation. Two Ki-67 isoforms with molecular weight, 395 and 345 kDa are known. Both isoforms contain 16 “Ki-67 repeat“ sequences, each of which includes a conserved 66 bp “Ki-67 motif“. Expression of Ki-67 protein is present during all active phases of the cell cycle (G(1), S, G(2), and mitosis), but is absent from resting cells (G(0)). Due to strict association of Ki-67 with proliferating cells, Ki-67 is often used as an indicator of the “growth fraction“ of a given cell population. The N-terminal portion of Ki-67 contains a forkhead associated (FHA)1 domain, which is involved in interaction with proteins such as Hklp2 and NIFK.
Additional information: Clone REA183 displays negligible binding to Fc receptors.

Alternative Names

MKI67, KIA, MIB-, MIB-1, PPP1R105, Ki67

Technical specifications

  • Antigen: Ki-67
  • Clone: REA183
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: MKI67, KIA, MIB-, MIB-1, PPP1R105, Ki67
  • Entrez Gene ID: 4288
  • Molecular mass of antigen [kDa]: 359
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC

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