Anti-iNKT antibodies, human

Anti-iNKT antibodies, human

Clone: 6B11 | Dilution: 1:11
NKT cells represent a distinct lymphocyte population that co-expresses T cell and NK cell surface markers. A subset of human NKT cells, referred to as iNKT cells, expresses an invariant TCR α-chain with certain TCR β-chains (Vα24-Jα18 combined with Vβ11). The iNKT cells are implicated in immunoregulatory processes such as tolerance, host defense, and tumor surveillance.

Technical specifications

  • Antigen: iNKT
  • Clone: 6B11
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Entrez Gene ID: 28659, 28747, 28582, 28581
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: NKT cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Exley, M. et al. (2008) Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR α-chain CDR3 loop. Eur. J. Immunol. 38: 1756-1766
    2. Montoya, J. C. et al. (2007) Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology 122: 1-14
Product options: 8
130-098-128

Anti-iNKT-PE, human

for 30
tests
(1)
-
130-094-838

Anti-iNKT-PE, human

for 100
tests
(1)
-
130-098-130

Anti-iNKT-APC, human

for 30
tests
(1)
-
130-094-839

Anti-iNKT-APC, human

for 100
tests
(1)
-
130-104-148

Anti-iNKT-PE-Vio770, human

for 30
tests
(1)
-
130-104-110

Anti-iNKT-PE-Vio770, human

for 100
tests
(1)
-
130-098-131

Anti-iNKT-Biotin, human

for 30
tests
(1)
-
130-094-841

Anti-iNKT-Biotin, human

for 100
tests
(1)
-