Anti-IL-8 antibodies, human

Anti-IL-8 antibodies, human

Clone: REA731 | Dilution: 1:50
Clone REA731 recognizes the human IL-8 chemokine, a heterodimer also known as interleukin 8 or CXCL8 (chemokine (C-X-C motif) ligand 8. IL-8 is secreted by macrophages, epithelial cells, airway smooth muscle cells, and endothelial cells. IL-8 plays a role in neutrophil activation, is a potent promoter of angiogenesis, and attracts neutrophils, basophils, and T cells. Clone REA731 recognizes both the 72 and 77 amino acid isoforms of human IL-8.
Additional information: Clone REA731 displays negligible binding to Fc receptors.

Alternative names

Interleukin-8, Emoctakin, GCP-1, MDNCF, MONAP, NAP-1, Protein 3-10C, CXCL8

Technical specifications

  • Antigen: IL-8
  • Clone: REA731
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: Interleukin-8, Emoctakin, GCP-1, MDNCF, MONAP, NAP-1, Protein 3-10C, CXCL8
  • Entrez Gene ID: 3576
  • Molecular mass of antigen [kDa]: 9
  • Distribution of antigen: neutrophils, basophils, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
  • Selected references

    1. Mukaida, N. et al. (1989) Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8. J. Immunol. 143(4): 1366-1371
    2. Matsushima, K. et al. (1989) Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL 1 and TNF. Cytokine 1(1): 2-13
    3. Hébert, C. A. et al. (1990) Endothelial and leukocyte forms of IL-8. Conversion by thrombin and interactions with neutrophils. J. Immunol. 145(9): 3033-3040
Product options: 6
130-112-014

Anti-IL-8-FITC, human

for 30
tests
(1)
-
130-111-862

Anti-IL-8-FITC, human

for 100
tests
(1)
-
130-112-015

Anti-IL-8-PE, human

for 30
tests
(1)
-
130-111-863

Anti-IL-8-PE, human

for 100
tests
(1)
-
130-112-016

Anti-IL-8-APC, human

for 30
tests
(1)
-
130-111-864

Anti-IL-8-APC, human

for 100
tests
(1)
-