Anti-IL-6 antibodies, mouse

Anti-IL-6 antibodies, mouse

Clone: MP5-20F3 | Dilution: 1:10
Interleukin 6 (IL-6), originally identified as a B cell differentiation factor, is a multifunctional cytokine, which regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions. It induces the terminal maturation of activated B cells into antibody-secreting plasma cells and acts in synergy with IL-3 to support the proliferation of hematopoietic stem cells. IL-6 is produced by many cell types, such as monocytes, fibroblasts, endothelial cells, eosinophils, and T cells. Disturbed IL-6 production has been associated with pathological processes, including inflammatory autoimmune diseases and cancer.

Technical specifications

  • Antigen: IL-6
  • Clone: MP5-20F3
  • Isotype: rat IgG1κ
  • Isotype control: Rat IgG1 – isotype control antibodies
  • Entrez Gene ID: 16193
  • Molecular mass of antigen [kDa]: 22
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
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