Anti-IL-2 antibodies – functional grade, mouse

Anti-IL-2 antibodies – functional grade, mouse

Clone: JES6-5H4
Interleukin 2 (IL-2) is produced by cells that are involved in inflammatory immune responses. IL-2 is rapidly secreted by naive CD4
+
T cells and by central memory T cells upon activation and promotes growth and differentiation of T cells and has pleiotropic effects on many other leukocytes. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. It has been found to stimulate growth and differentiation of B cells, NK cells, monocytes, and oligodendrocytes. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance, and anti-inflammatory reactions.

Applications

The Anti-IL-2 pure – functional grade antibody is suited for functional assays, for example, neutralization of IL-2 activity.

Technical specifications

  • Antigen: IL-2
  • Clone: JES6-5H4
  • Isotype: rat IgG2bκ
  • Entrez Gene ID: 16183
  • Molecular mass of antigen [kDa]: 17
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
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