Anti-IL-17RC antibodies, human

Anti-IL-17RC antibodies, human

Clone: REA571 | Dilution: 1:11
Clone REA571 recognizes the human IL-17RC antigen, a single-pass transmembrane protein belonging to the IL-17 cytokine family. The IL-17 receptor (IL-17R) subfamily includes IL-17RA, IL-17RB, IL-17RC, IL-17RD, and IL-17RE that induce signaling via recruitment of signaling intermediates. Together with IL-17RA IL-17RC is able to form a receptor complex capable specific for IL-17A and IL-17F. IL-17RC is expressed in prostate and prostate cancer, skeletal muscle, kidney, and placenta.
Additional information: Clone REA571 displays negligible binding to Fc receptors.

Alternative names

CANDF9, IL17-RL

Technical specifications

  • Antigen: IL-17RC
  • Clone: REA571
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CANDF9, IL17-RL
  • Entrez Gene ID: 84818
  • Molecular mass of antigen [kDa]: 84
  • Distribution of antigen: prostate cancer cells, skeletal muscle, kidney, placenta
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Haudenschild, D. et al. (2002) Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer. J. Biol. Chem. 277(6): 4309-4316
    2. Toy, D. et al. (2006) Cutting edge: interleukin 17 signals through a heteromeric receptor complex. J. Immunol. 177(1): 36-39
    3. Kuestner, R. E. et al. (2007) Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F. J. Immunol. 179(8): 5462-5473
    4. Ho, A. W. et al. (2010) IL-17RC: a partner in IL-17 signaling and beyond. Semin. Immunol. 32(1): 33-42
Product options: 8
130-109-196

Anti-IL-17RC-FITC, human

for 30
tests
(1)
-
130-109-149

Anti-IL-17RC-FITC, human

for 100
tests
(1)
-
130-109-197

Anti-IL-17RC-PE, human

for 30
tests
(1)
-
130-109-150

Anti-IL-17RC-PE, human

for 100
tests
(1)
-
130-109-198

Anti-IL-17RC-APC, human

for 30
tests
(1)
-
130-109-151

Anti-IL-17RC-APC, human

for 100
tests
(1)
-
130-109-195

Anti-IL-17RC-Biotin, human

for 30
tests
(1)
-
130-109-148

Anti-IL-17RC-Biotin, human

for 100
tests
(1)
-