Anti-IL-13 antibodies – functional grade, human

Anti-IL-13 antibodies – functional grade, human

Clone: JES10-5A2.2
Interleukin-13 (IL-13) is produced primarily by activated Tʜ2 cells, but also by mast cells, NK cells, and dendritic cells. IL-13 exerts anti-inflammatory effects on monocytes and macrophages. Furthermore, it inhibits the expression of pro-inflammatory cytokines, such as IL-1β, TNF-α, IL-6, and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in an increased production of IgE.
IL-13, in contrast to IL-4, fails to induce Tʜ2 cell differentiation, one of the hallmarks of the allergic response.

Applications

This pure – functional grade antibody is suited for functional assays, for example, neutralization of cytokine activity.

Alternative Names

P600

Technical specifications

  • Antigen: IL-13
  • Clone: JES10-5A2.2
  • Isotype: rat IgG1
  • Alternative names of antigen: P600
  • Entrez Gene ID: 3596
  • Molecular mass of antigen [kDa]: 13
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
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