Anti-IFN-γR β chain-antibodies, mouse

Anti-IFN-γR β chain-antibodies, mouse

Clone: REA381 | Dilution: 1:10
Clone REA381 recognizes the mouse IFN-γ receptor β chain antigen, a type 1 transmembrane protein also known as IFN-γ accessory factor 1 (AF-1). The IFN-γR β chain pairs with CD119 to form the IFN-γ receptor. It is expressed at low levels on T and B cells, NK cells, monocytes, macrophages, and fibroblasts. IFN-γ induces several biologic effects in target cells, including antiviral and antiproliferative responses, expression of major histocompatibility complex and of Fc receptor genes, and immunoglobulin class switching.
Additional information: Clone REA381 displays negligible binding to Fc receptors.

Alternative Names

IFNGR2, IFGR2, Ifgt, AF-1, IFNGRB, IFNGT1, IFNγ R2, IFNγ Rβ

Technical specifications

  • Antigen: IFN-γR β chain
  • Clone: REA381
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: IFNGR2, IFGR2, Ifgt, AF-1, IFNGRB, IFNGT1, IFNγ R2, IFNγ Rβ
  • Entrez Gene ID: 15980
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: T cells, B cells, NK cells, macrophages, monocytes, fibroblasts, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
  • Selected References

    1. Marsters, S. A. et al. (1995) Interferon gamma signals via a high-affinity multisubunit receptor complex that contains two types of polypeptide chain. Proc. Natl. Acad. Sci. U.S.A. 92(12): 5401-5405
    2. Hemmi, S. et al. (1994) A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in human cells. Cell 76(5): 803-810
    3. Ebensperger, C. et al. (1996) Genomic organization and promoter analysis of the gene ifngr2 encoding the second chain of the mouse interferon-gamma receptor. Scand. J. Immunol. 44(6): 599-606
Product options: 8

Product information

Size
Order no.
Price

Anti-IFN-γR β chain-PE, mouse

  • REA381
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-105-718
-

Anti-IFN-γR β chain-PE, mouse

  • REA381
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-105-671
-

Anti-IFN-γR β chain-APC, mouse

  • REA381
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-105-719
-

Anti-IFN-γR β chain-APC, mouse

  • REA381
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-105-672
-

Anti-IFN-γR β chain-PE-Vio770, mouse

  • REA381
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-105-720
-

Anti-IFN-γR β chain-PE-Vio770, mouse

  • REA381
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-105-673
-

Anti-IFN-γR β chain-Biotin, mouse

  • REA381
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-105-717
-

Anti-IFN-γR β chain-Biotin, mouse

  • REA381
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-105-670
-