Anti-I-Aq antibodies, mouse

Anti-I-Aq antibodies, mouse

Clone: REA478 | Dilution: 1:10
Clone REA478 recognizes the mouse I-Aq MHC class II alloantigen. It also recognizes with I-As and I-Av.1. Reactivity with other haplotypes has not been reported. MHC (major histocompatibility complex) class II molecules are a family of molecules normally found on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells. Because class II MHC is loaded with extracellular proteins, it is mainly concerned with presentation of extracellular pathogens.
Additional information: Clone REA478 displays negligible binding to Fc receptors.

Alternative Names

MHC class II

Technical specifications

  • Antigen:
  • Clone: REA478
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: MHC class II
  • Entrez Gene ID: 14961
  • Molecular mass of antigen [kDa]: 27
  • Distribution of antigen: B cells, dendritic cells, endothelial cells, macrophages, monocytes, thymic epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
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