Anti-HLA-DR antibodies, human

Anti-HLA-DR antibodies, human

Clone: REA805 | Dilution: 1:50
Clone REA805 recognizes the human major histocompatibility (MHC) class II antigen HLA-DR, a heterodimeric cell surface glycoprotein belonging to the Ig superfamiliy. HLA-DR is constitutively expressed on professional antigen-presenting cells like dendritic cells, B cells, and monocytes/macrophages. Its expression is further up-regulated upon activation. On T cells, NK cells, hematopoietic precursor cells, and some epithelial cells the expression of HLA-DR is induced by cell activation.
Additional information: Clone REA805 displays negligible binding to Fc receptors.

Alternative Names

HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5
REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the other known clones. 
Other clonesOverlap in epitope recognition with REA805
L243++
LN3-
AC122++
REA332-
Tü39-
Tü36-

Technical specifications

  • Antigen: HLA-DR
  • Clone: REA805
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5
  • Entrez Gene ID: 3123, 3122, 3127, 3126, 3125
  • Molecular mass of antigen [kDa]: 27-33
  • Cross-reactivity:
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    african green monkey (
    Chlorocebus aethiops
    )
    , baboon,
    chimpanzee (
    Pan troglodytes
    )
    ,
    common marmoset (
    Callithrix jacchus
    )
    ,
    cotton-top tamarin (
    Saguinus oedipus
    )
    ,
    pigtail monkey (
    Macaca nemestrina
    )
  • Distribution of antigen: dendritic cells, B cells, monocytes, macrophages
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
Product options: 20

Product information

Size
Order no.
Price

Anti-HLA-DR-FITC, human

  • REA805
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-941
-

Anti-HLA-DR-FITC, human

  • REA805
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-788
-

Anti-HLA-DR-PE, human

  • REA805
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-942
-

Anti-HLA-DR-PE, human

  • REA805
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-789
-

Anti-HLA-DR-APC, human

  • REA805
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-943
-

Anti-HLA-DR-APC, human

  • REA805
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-790
-

Anti-HLA-DR-VioBlue, human

  • REA805
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-947
-

Anti-HLA-DR-VioBlue, human

  • REA805
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-794
-

Anti-HLA-DR-VioGreen, human

  • REA805
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-948
-

Anti-HLA-DR-VioGreen, human

  • REA805
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-795
-

Anti-HLA-DR-PE-Vio615, human

  • REA805
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-950
-

Anti-HLA-DR-PE-Vio615, human

  • REA805
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-797
-

Anti-HLA-DR-PE-Vio770, human

  • REA805
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-944
-

Anti-HLA-DR-PE-Vio770, human

  • REA805
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-791
-

Anti-HLA-DR-APC-Vio770, human

  • REA805
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-945
-

Anti-HLA-DR-APC-Vio770, human

  • REA805
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-792
-

Anti-HLA-DR-PerCP-Vio700, human

  • REA805
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-946
-

Anti-HLA-DR-PerCP-Vio700, human

  • REA805
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-793
-

Anti-HLA-DR-Biotin, human

  • REA805
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-940
-

Anti-HLA-DR-Biotin, human

  • REA805
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-787
-

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