Anti-HLA-DR antibodies, human

Anti-HLA-DR antibodies, human

Clone: AC122
Anti-HLA-DR antibodies react with the human major histocompatibility (MHC) class II antigen HLA-DR. HLA-DR is constitutively expressed on professional antigen-presenting cells like dendritic cells, B cells, and monocytes/macrophages. Its expression is further up-regulated upon activation. On T cells, NK cells, hematopoietic precursor cells, and some epithelial cells the expression of HLA-DR is induced by cell activation.

Alternative Names

HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5

Technical specifications

  • Antigen: HLA-DR
  • Clone: AC122
  • Isotype: mouse IgG2a
  • Isotype control: Mouse IgG2a – isotype control antibodies
  • Alternative names of antigen: HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5
  • Entrez Gene ID: 3123, 3122, 3127, 3126, 3125, 16149
  • Molecular mass of antigen [kDa]: 27-33
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    african green monkey (
    Chlorocebus aethiops
    )
    ,
    common marmoset (
    Callithrix jacchus
    )
    , guinea pig
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
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