Anti-HLA-ABC antibodies, human

Anti-HLA-ABC antibodies, human

Clone: REA230 | Dilution: 1:11
Clone REA230 recognizes a monomorphic epitope on MHC class I molecules, HLA A, B, and C. MHC class I molecules are expressed by all human nucleated cells and are involved in presentation of peptide ligands on the cell surface for recognition by cytotoxic T cells.
Additional information: Clone REA230 displays negligible binding to Fc receptors.

Alternative names

HLA-A, HLA-B, HLA-C, AS, SPDA1, D6S204, HLA-JY3, HLC-C, PSORS1

Technical specifications

  • Antigen: HLA-ABC
  • Clone: REA230
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: HLA-A, HLA-B, HLA-C, AS, SPDA1, D6S204, HLA-JY3, HLC-C, PSORS1
  • Entrez Gene ID: 3105, 3106, 3107
  • Molecular mass of antigen [kDa]: 38
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    olive baboon (
    Papio anubis
    )
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, APC, PerCP-Vio700

Specificity

In order to compare the epitope specificity of REAfinity Clone REA230 with other known clones, a competition assay was performed.
 Cells were incubated with an excess of purified unconjugated REAfinity Antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or completely different epitopes (-) of the marker.
 

Other clonesOverlap in epitope recognition with REA230
G46-2.6++
W6/32++
Product options: 4
130-101-466

Anti-HLA-ABC-APC, human

for 30
tests
(1)
-
130-101-467

Anti-HLA-ABC-APC, human

for 100
tests
(1)
-
130-101-453

Anti-HLA-ABC-PerCP-Vio700, human

for 30
tests
(1)
-
130-101-461

Anti-HLA-ABC-PerCP-Vio700, human

for 100
tests
(1)
-