Anti-H60a antibodies, mouse

Anti-H60a antibodies, mouse

Clone: REA556 | Dilution: 1:10
Clone REA556 recognizes the mouse H60a antigen, a histocompatibility antigen expressed in BALB but not C57BL/6 mouse strains. H60a is expressed on haematopoietic cells and is also is found on tumor cells that constitutively express H60a at the cell surface. H60a is recognized by H60a-specific CD8
+
T cells. H60a also binds natural killer group 2, member D (NKG2D) and can participate in tumor surveillance and cancer immunoediting. H60a is up-regulated by certain stimuli including DNA damage and virus infection.
Additional information: Clone REA556 displays negligible binding to Fc receptors.

Alternative Names

H60

Technical specifications

  • Antigen: H60a
  • Clone: REA556
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: H60
  • Entrez Gene ID: 15101
  • Molecular mass of antigen [kDa]: 28
  • Distribution of antigen: hematopoietic cells, T cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
  • Selected references

    1. Guerra, N. et al. (2008) NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity 28(4): 571-580
    2. Samarakoon, A. et al. (2009) Murine NKG2D ligands: "double, double toil and trouble". Mol. Immunol. 46(6): 1011-1019
    3. Yadav, D. et al. (2011) Studies on the antigenicity of the NKG2D ligand H60a in tumour cells. Immunology 133(2): 197-205
Product options: 4
130-108-846

Anti-H60a-PE, mouse

9 µg in 300 µL (1)
-
130-108-820

Anti-H60a-PE, mouse

30 µg in 1 mL (1)
-
130-108-847

Anti-H60a-APC, mouse

9 µg in 300 µL (1)
-
130-108-821

Anti-H60a-APC, mouse

30 µg in 1 mL (1)
-