Anti-GM-CSF antibodies – functional grade, human

Anti-GM-CSF antibodies – functional grade, human

Clone: BVD2-21C11
Granulocyte macrophage colony-stimulating factor (GM‑CSF) is a hematopoietic growth factor that is essential for proliferation and development of granulocyte and monocyte/macrophage progenitors. It also functions as a growth factor for erythroid and megakaryocytic precursor cells in conjunction with erythropoietin. GM-CSF is secreted by various cell types including T cells, macrophages, endothelial cells, and fibroblasts in response to inflammatory stimuli and cytokines. In addition, GM-CSF strongly chemoattracts neutrophils and eosinophils and enhances the effector functions of neutrophils and macrophages.

Applications

This pure – functional grade antibody is suited for functional assays, for example, neutralization of cytokine activity.

Alternative Names

CSF2, GM-CSF

Technical specifications

  • Antigen: GM-CSF
  • Clone: BVD2-21C11
  • Isotype: rat IgG2aκ
  • Alternative names of antigen: CSF2, GM-CSF
  • Entrez Gene ID: 1437
  • Molecular mass of antigen [kDa]: 14
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
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