Anti-Galectin-3 antibodies, human and mouse

Anti-Galectin-3 antibodies, human and mouse

Clone: REA1072 | Dilution: 1:50
Clone REA1072 recognizes mouse and human galectin-3, which is a 32 kDa protein belonging to the beta-galactoside-binding animal lectin family. Galectin-3, also known as Mac-2, has an IgE-binding activity and is localized in Kupffer cells, macrophages, human peripheral blood monocytes, and murine activated T cells. An upregulated expression of galectin-3 is observed during cell proliferation, differentiation, and inflammation.
Additional information: Clone REA1072 displays negligible binding to Fc receptors.

Alternative names

LGALS3, CBP35, GAL3, GALBP, L31, LGALS2, Mac-2

Technical specifications

  • Antigen: Galectin-3
  • Clone: REA1072
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: LGALS3, CBP35, GAL3, GALBP, L31, LGALS2, Mac-2
  • Entrez Gene ID: 16854, 3958
  • Molecular mass of antigen [kDa]: 26
  • Distribution of antigen: macrophages, monocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
  • Selected references

    1. Springer, T. A. et al. (1981) Monoclonal antibody analysis of complex biological systems. Combination of cell hybridization and immunoadsorbents in a novel cascade procedure and its application to the macrophage cell surface. J. Biol. Chem. 256: 3833-3839
    2. Ho, M. K. and Springer, T. A. et al. (1982) Mac-2, a novel 32,000 Mr mouse macrophage subpopulation-specific antigen defined by monoclonal antibodies. J. Immunol. 128: 1221-1228
    3. Liu, F. T. et al. (1995) Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages. Am. J. Pathol. 147(4): 1016-1028
    4. Joo, H. G. et al. (2001) Expression and function of galectin-3, a ß-galactoside-binding protein in activated T lymphocytes. J. Leukoc. Biol. 69: 555-564
Product options: 6
130-118-769

Anti-Galectin-3-FITC, human and mouse

for 30
tests
(1)
-
130-118-647

Anti-Galectin-3-FITC, human and mouse

for 100
tests
(1)
-
130-118-770

Anti-Galectin-3-PE, human and mouse

for 30
tests
(1)
-
130-118-648

Anti-Galectin-3-PE, human and mouse

for 100
tests
(1)
-
130-118-771

Anti-Galectin-3-APC, human and mouse

for 30
tests
(1)
-
130-118-649

Anti-Galectin-3-APC, human and mouse

for 100
tests
(1)
-