Anti-Galectin-3 antibodies, human and mouse

Anti-Galectin-3 antibodies, human and mouse

Clone: M3/38 | Dilution: 1:10
The monoclonal antibody M3/38 recognizes mouse and human galectin-3, which is a 32 kDa protein belonging to the beta-galactoside-binding animal lectin family. Galectin-3, also known as Mac-2, has an IgE-binding activity and is localized in Kupffer cells, macrophages, human peripheral blood monocytes, and murine activated T cells. An upregulated expression of galectin-3 is observed during cell proliferation, differentiation, and inflammation.

Alternative Names

LGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, Mac-2

Technical specifications

  • Antigen: Galectin-3
  • Clone: M3/38
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: LGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, Mac-2
  • Distribution of antigen: macrophages, monocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
  • Selected references

    1. Ho, M. K. and Springer, T. A. et al. (1982) Mac-2, a novel 32,000 Mr mouse macrophage subpopulation-specific antigen defined by monoclonal antibodies. J. Immunol. 128: 1221-1228
    2. Springer, T. A. et al. (1981) Monoclonal antibody analysis of complex biological systems. Combination of cell hybridization and immunoadsorbents in a novel cascade procedure and its application to the macrophage cell surface. J. Biol. Chem. 256: 3833-3839
    3. Joo, H. G. et al. (2001) Expression and function of galectin-3, a ß-galactoside-binding protein in activated T lymphocytes. J. Leukoc. Biol. 69: 555-564
    4. Liu, F. T. et al. (1995) Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages. Am. J. Pathol. 147(4): 1016-1028
Product options: 6
130-101-314

Anti-Galectin-3-PE, human and mouse

for 30
tests
(1)
-
130-101-315

Anti-Galectin-3-PE, human and mouse

for 100
tests
(1)
-
130-101-313

Anti-Galectin-3-APC, human and mouse

for 30
tests
(1)
-
130-101-312

Anti-Galectin-3-APC, human and mouse

for 100
tests
(1)
-
130-113-035

Anti-Galectin-3-Biotin, human and mouse

for 30
tests
(1)
-
130-112-969

Anti-Galectin-3-Biotin, human and mouse

for 100
tests
(1)
-