Anti-fMLP receptor antibodies, human

Anti-fMLP receptor antibodies, human

Clone: REA169 | Dilution: 1:11
Clone REA169 recognizes N-formyl-L-methionyl-L-leucyl-phenylalanine receptor (fMLP receptor), which is a seven transmembrane G-protein coupled receptor. fMLP receptor binds formylated peptides such as fMLP, which originate from degraded bacterial or mitochondrial proteins and mediate inflammatory reactions, activation of neutrophils and trafficking of leukocytes to the site of inflammation. Expression of fMLP receptor is mainly found on leukocytes, neutrophils and monocytes.
Additional Information: Clone REA169 displays negligible binding to Fc receptors.

Alternative names

FPR1, FMLP, FPR

Technical specifications

  • Antigen: fMLP receptor
  • Clone: REA169
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: FPR1, FMLP, FPR
  • Entrez Gene ID: 2357
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: monocytes, macrophages, neutrophils
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
  • Selected references

    1. Paclet, M. H. et al. (2004) N-Formyl peptide receptor subtypes in human neutrophils activate L-plastin phosphorylation through different signal transduction intermediates. Biochem. J. 377: 469-477
Product options: 6
130-100-817

Anti-fMLP receptor-FITC, human

for 30
tests
(1)
-
130-100-814

Anti-fMLP receptor-FITC, human

for 100
tests
(1)
-
130-100-820

Anti-fMLP receptor-PE, human

for 30
tests
(1)
-
130-100-821

Anti-fMLP receptor-PE, human

for 100
tests
(1)
-
130-100-813

Anti-fMLP receptor-APC, human

for 30
tests
(1)
-
130-100-812

Anti-fMLP receptor-APC, human

for 100
tests
(1)
-