Anti-FcεRIα antibodies – functional grade, mouse

Anti-FcεRIα antibodies – functional grade, mouse

Clone: MAR-1
Clone MAR-1 detects the alpha subunit of the murine high-affinity Fc receptor for IgE. The receptor is composed of one alpha-, one beta-, and two disulfid-linked gamma subunits, of which the alpha subunit binds IgE. FcεRIα is expressed on mast and basophilic cells and is up-regulated in the presence of IgE. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions.

Applications

The Anti-FcεRIα pure – functional grade antibody is suited for functional assays, for example, blocking of receptor-ligand binding.

Alternative Names

FCER1A, FcERI, Fce1a, Fcr-5

Technical specifications

  • Antigen: FcεRIα
  • Clone: MAR-1
  • Isotype: hamster IgG
  • Alternative names of antigen: FCER1A, FcERI, Fce1a, Fcr-5
  • Entrez Gene ID: 14125
  • Molecular mass of antigen [kDa]: 26
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
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