Anti-Dectin-2 antibodies, mouse

Anti-Dectin-2 antibodies, mouse

Clone: REA1001 | Dilution: 1:50
Clone REA1001 recognizes the mouse dendritic cell–associated C-type lectin 2 (dectin-2) antigen. Dectin-2 is a type II membrane protein and contains a single carbohydrate recognition domain. Like other C-type lectins, mouse dectin-2 has conserved motifs for the Ca
2+
-dependent recognition of mannose. Dectin-2 is located in the natural killer gene complex of chromosome 6. Genomic analyses show that beside a full length dectin-2 transcript two truncated isoforms are produced by alternative splicing, encoding transmembrane proteins of 168–209 amino acids. The expression of dectin-2 on mouse monocytes and macrophages can be induced by zymosan and thioglycollate. Dectin-2 plays a physiological role in antigen presentation and antigen targeting via dectin-2 can induce a CD8
+
T cell response.
Additional information: Clone REA1001 displays negligible binding to Fc receptors.

Alternative Names

CLEC4N, Clec6a, Clecsf10, Nkcl

Technical specifications

  • Antigen: Dectin-2
  • Clone: REA1001
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CLEC4N, Clec6a, Clecsf10, Nkcl
  • Entrez Gene ID: 56620
  • Molecular mass of antigen [kDa]: 24
  • Distribution of antigen: macrophages, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
Product options: 2

Product information

Size
Order no.
Price

Anti-Dectin-2-PE, mouse

  • REA1001
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-910
-

Anti-Dectin-2-APC, mouse

  • REA1001
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-911
-