Anti-DAP12 antibodies, human

Anti-DAP12 antibodies, human

Clone: REA900 | Dilution: 1:50
Clone REA900 recognizes the human DAP12 antigen, a transmembrane signaling polypeptide which consists of an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. DAP12 interacts with several members of the CD300 molecule-like family, CLECSF5 and Siglec14. The association of DAP12 with triggering receptor expressed on myeloid cells (TREM-1) and myeloid DAP12-associating lectin (MDL-1) plays a role in monocytic activation and inflammatory response. DAP12 is found in several tissues, but also in peripheral blood leukocytes.
Additional information: Clone REA900 displays negligible binding to Fc receptors.

Alternative Names


Technical specifications

  • Antigen: DAP12
  • Clone: REA900
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: KARAP, TYROBP
  • Entrez Gene ID: 7305
  • Molecular mass of antigen [kDa]: 10
  • Distribution of antigen: brain, spleen, leukocytes, monocytes, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC

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