Anti-CXCL9 (MIG) antibodies, mouse

Anti-CXCL9 (MIG) antibodies, mouse

Clone: REA365 | Dilution: 1:10
Clone REA365 recognizes the mouse C-X-C motif chemokine ligand 9 (CXCL9) antigen, a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by interferon γ (MIG). CXCL9 is a T-cell chemoattractant, which is induced by IFN-γ during infection, injury or immunoinflammatory responses in macrophages, hepatocytes, and endothelial cells. It is best known for its role in leucocyte trafficking, principally acting on activated CD4
+
Th1 cells, CD8
+
T cells and NK cells. CXCL9 also has angiostatic properties. Overexpression of CXCL9 in tumors can lead to T-cell accumulation, vascular damage, and tumor regression. It elicits its chemotactic functions by interacting with the chemokine receptor CXCR3.
Additional information: Clone REA365 displays negligible binding to Fc receptors.

Alternative Names

CMK, γ-interferon-induced monokine, MuMIG, Scyb9, crg-10, MIG

Technical specifications

  • Antigen: CXCL9 (MIG)
  • Clone: REA365
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CMK, γ-interferon-induced monokine, MuMIG, Scyb9, crg-10, MIG
  • Entrez Gene ID: 17329
  • Molecular mass of antigen [kDa]: 12
  • Distribution of antigen: T cells, macrophages, endothelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
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