Anti-CX3CR1 antibodies, human

Anti-CX3CR1 antibodies, human

Clone: 2A9-1 | Dilution: 1:11
CX3CR1 is a transmembrane chemokine receptor with a molecular mass of 40 kDa. It binds the chemokine CX3CL1, also known as fractalkine or neurotactin. Binding of CX3CR1 to the membrane‑bound form of fractalkine promotes cell-cell adhesion, wheras the soluble form induces cell migration of CX3CR1-bearing cells such as monocytes, NK cells, T cells, dendritic cells (DCs), and macrophages including microglia.¹ CX3CR1 plays also an important role in the formation of transepithelial dendrites by intestinal DCs.² Failure in the fractalkine/CX3CR1 interaction may contribute to the development of several inflammatory diseases including atherosclerosis, psoriasis, rheumatoid arthritis, and experimental autoimmune myositis.

Alternative Names


Technical specifications

  • Antigen: CX3CR1
  • Clone: 2A9-1
  • Isotype: rat IgG2bκ
  • Isotype control: Rat IgG2b – isotype control antibodies
  • Alternative names of antigen: CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28
  • Entrez Gene ID: 1524
  • Molecular mass of antigen [kDa]: 40
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
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