Anti-Claudin-3 antibodies, human

Anti-Claudin-3 antibodies, human

Clone: REA751 | Dilution: 1:50
Clone REA751 recognizes the human claudin-3 antigen, an integral membrane protein which is a component of the claudin family of epithelial tight junction proteins. Claudin-3 is involved in tight junction-specific obliteration of the intercellular space. It is a low-affinity receptor for
Clostridium perfringens
enterotoxinin (CPE). Binding of CPE to claudin-3 induces epithelial cell lysis.
Additional information: Clone REA751 displays negligible binding to Fc receptors.

Alternative names

CPE-R 2, hRVP1, CLDN3, C7orf1, CPETR2

Technical specifications

  • Antigen: Claudin-3
  • Clone: REA751
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CPE-R 2, hRVP1, CLDN3, C7orf1, CPETR2
  • Distribution of antigen: epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
  • Selected references

    1. Morita, K. et al. (1999) Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc. Natl. Acad. Sci. U.S.A. 96(2): 511-516
    2. Furuse, M. et al. (1999) Manner of interaction of heterogeneous claudin species within and between tight junction strands. J. Cell Biol. 147(4): 891-903
    3. Coyne, C. B. et al. (2003) Role of claudin interactions in airway tight junctional permeability. Am. J. Physiol. Lung Cell Mol. Physiol. 285(5): 1166-1178
Product options: 6
130-110-834

Anti-Claudin-3-PE, human

for 30
tests
(1)
-
130-110-696

Anti-Claudin-3-PE, human

for 100
tests
(1)
-
130-110-835

Anti-Claudin-3-APC, human

for 30
tests
(1)
-
130-110-697

Anti-Claudin-3-APC, human

for 100
tests
(1)
-
130-110-833

Anti-Claudin-3-Biotin, human

for 30
tests
(1)
-
130-110-695

Anti-Claudin-3-Biotin, human

for 100
tests
(1)
-