Anti-Cadherin-13 antibodies, human

Anti-Cadherin-13 antibodies, human

Clone: REA752 | Dilution: 1:50
Clone REA752 recognizes the human cadherin-13 antigen, also known as T-Cadherin or H-Cadherin (heart cadherin). Cadherin-13 is a transmembrane glycoprotein that mediates calcium-dependent intercellular adhesion.
It is suggested that cadherin-13 may function as a negative regulator of neural cell growth. Cadherin-13 is expressed human adult cerebral cortex, medulla, thalamus, and midbrain. In developing brain, a lower expression is found than in adult brain. Furthermore, cadherin-13 is expressed in the basal layer of the epidermis, lung, liver, kidney, and blood vessels. It is reported, that cadherin-13 could be used as a marker for breast cancer development.
Additional information: Clone REA752 displays negligible binding to Fc receptors.

Alternative Names

p150, T-cad, T-cadherin

Technical specifications

  • Antigen: Cadherin-13
  • Clone: REA752
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: p150, T-cad, T-cadherin
  • Entrez Gene ID: 1012
  • Molecular mass of antigen [kDa]: 61
  • Cross-reactivity: mouse
  • Distribution of antigen: brain
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, Biotin
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