Anti-Bcl-6 antibodies, human and mouse

Anti-Bcl-6 antibodies, human and mouse

Clone: REA373 | Dilution: 1:11
Clone REA373 recognizes the human and mouse Bcl-6 antigen, a member of the BTB-zinc finger family of proteins. Bcl-6 is a transcriptional repressor, expressed in germinal center T and B cells and in primary immature dendritic cells. It plays critical functions in various cell types within the adaptive and innate compartments of the immune system. Bcl-6 is highly up-regulated in B cells after T cell–dependent antigenic challenge, and is required for formation of germinal centers within which B cells undergo immunoglobulin affinity maturation. It also plays an important role in macrophages, where it mediates a dampening effect on inflammatory signaling through repression of chemokine expression and NF-κB target genes.
Additional information: Clone REA373 displays negligible binding to Fc receptors.

Alternative Names

BCL6, BCL5, BCL6A, LAZ3, ZBTB27, ZNF51

Technical specifications

  • Antigen: Bcl-6
  • Clone: REA373
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: BCL6, BCL5, BCL6A, LAZ3, ZBTB27, ZNF51
  • Entrez Gene ID: 604, 12053
  • Molecular mass of antigen [kDa]: 79
  • Distribution of antigen: T cells, B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
Product options: 4

Product information

Size
Order no.
Price

Anti-Bcl-6-PE, human and mouse

  • REA373
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-486
-

Anti-Bcl-6-PE, human and mouse

  • REA373
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-443
-

Anti-Bcl-6-APC, human and mouse

  • REA373
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-485
-

Anti-Bcl-6-APC, human and mouse

  • REA373
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-442
-

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