Anti-AN2 antibodies, human and mouse

Anti-AN2 antibodies, human and mouse

Clone: 1E6.4 | Dilution: 1:11
AN2 is the mouse homolog of the rat NG2 and human MCSP proteins. NG2 is a chondroitin sulfate glycoprotein that is expressed by glial progenitor cells in the developing and adult central nervous system (CNS) and by immature Schwann cells. NG2/AN2
glia has been identified as a fourth major glial cell type in the mammalian CNS that is distinct from other cell types. NG2/AN2
cells are precursors of oligodendrocytes and some protoplasmic astrocytes in the gray matter. NG2/AN2 expression is down-regulated before the cells undergo terminal differentiation. However, a population of NG2/AN2
cells remains in the white and gray matter after oligodendrocytes are generated. NG2/AN2
glial cells participate in neuron-glial circuits by receiving presynaptic input from neurons and responding to neurotransmitters released by synapses. Many highly migratory neural tumors including melanomas express NG2/AN2.

Alternative Names


Technical specifications

  • Antigen: AN2
  • Clone: 1E6.4
  • Isotype: rat IgG1
  • Isotype control: Rat IgG1 – isotype control antibodies
  • Alternative names of antigen: CSPG4, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2
  • Entrez Gene ID: 1464
  • Molecular mass of antigen [kDa]: 248
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, Biotin, pure
Product options: -

Product information

Order no.

Related products

2 products available