CD326 (EpCAM) MicroBeads, mouse

CD326 (EpCAM) MicroBeads, mouse

CD326 (EpCAM) MicroBeads have been developed for positive selection or depletion of epithelial cells or epithelial tumor cells comprising from single-cell preparation of tissues and organs expressing mouse CD326 (EpCAM) antigen.

Background information

CD326, also known as epithelial cell adhesion molecule (EpCAM), is seen in the majority of carcinomas. It is expressed on cells of epithelial origin, epithelium-derived tumor cells
1
, circulating tumor cells, and cancer stem cells. Moreover , EpCAM is expressed on mouse embryonic stem cells and was described as a marker for the identification of successfully reprogrammed induced pluripotent stem cells (iPS)
2
.

Downstream applications

Tumor cells enriched by CD326 (EpCAM) MicroBeads can be cultured
3
and analyzed by immunocytochemistry
4
, flow cytometry, or molecular biology techniques, for example, RT-PCR
5
.

Columns

MS, LS, XS, or autoMACS
®
Columns.
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