Anti-Siglec-F MicroBeads, mouse

Anti-Siglec-F MicroBeads, mouse

The Anti-Siglec-F MicroBeads, mouse have been developed for the positive selection or depletion of cells expressing mouse Siglec-F antigen from mouse peripheral blood (eosinophils, minor fraction of neutrophils) or mouse lung single-cell suspensions (eosinophils and alveolar macrophages).

Background information

Siglec-F, also known as Siglec-5, is a member of the sialic acid-binding immunoglobulin (Ig)-like lectins (Siglecs). The extracellular Ig domain binds specifically carbohydrate structures containing sialic acid residues. Siglec-F has, like most Siglecs, an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain and is discussed to play a role in eosinophil accumulation and survival. It is expressed in a tissue dependent manner on most eosinophils, but also found on alveolar macrophages and some neutrophils.
Product options: 1

Product information

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Anti-Siglec-F MicroBeads, mouse

  • For research use only
for 1×
10
9
total cells
(1) or for 2×
10
9
cells
(2)
130-118-513
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