Anti-PSA-NCAM MicroBead Kit, human and mouse

Anti-PSA-NCAM MicroBead Kit, human and mouse

The Anti-PSA-NCAM MicroBead kit has been designed for the isolation of PSA-NCAM
+
neural progenitors from differentiated ES or iPS cell cultures.

Background information

The Anti-PSA-NCAM antibody recognizes an epitope on polysialic acid (PSA) which, in vertebrates, is found linked to the extracellular domain of the neural cell adhesion molecule (NCAM, CD56).¹ PSA-NCAM, the highly polysialated form of NCAM, is predominantly expressed
in embryonic and neonatal neural tissue.² In vitro differentiation of human and mouse pluripotent stem cells under defined conditions revealed that neuronal progenitors, e.g. long-term self-renewing neuroepithelial-like stem cells, express the surface marker PSA-NCAM.³ Magnetically enriched, in vitro generated PSA-NCAM positive neural progenitors can be further differentiated into defined neuronal subtypes.

Columns

LS or autoMACS
®
Columns.
Product options: 1

Product information

Size
Order no.
Price

Anti-PSA-NCAM MicroBead Kit, human and mouse

  • For research use only
for 1×
10
9
total cells
130-097-859
-