Mouse IL-5 Secretion Assay – Cell Enrichment and Detection Kit (PE)

Mouse IL-5 Secretion Assay – Cell Enrichment and Detection Kit (PE)

The Mouse IL-5 Secretion Assay - Cell Enrichment and Detection Kit was developed for the sensitive detection as well as the enrichment of murine IL-5-secreting cells.

Background information

Interleukin-5 (IL-5) is predominantly secreted by CD4
+
T cells. It promotes growth and activation of eosinophils, is involved in a range of allergic reactions, and mediates immune reactions against parasites. IL-5 also acts on other cell types such as B cells.

Downstream applications

The Mouse IL-5 Secretion Assays can be used to detect and isolate murine antigen-specific, IL-5-secreting T cells after stimulation with antigen (fig. 1). The assays allow studies on T
H
2 development and commitment as well as on the mechanism of IL-5 expression.

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MS, LS, or autoMACS
®
Columns.
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